Guido K.W. Frank @GuidoFrank
San Diego, CA Joined February 2009-
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@DrCarolLow @Metabolic_Mind @UCSDMedSchool It is not an easy step in the beginning, but typically in a short period of time, people can feel the difference and the benefits. And that is what keeps them engaged in this treatment.
Very much agreed, we are exploring in parallel brain glucose metabolism, as biological marker, as well as test the efficacy of ketogenic nutrition in different weight groups, and have also started studying the effects of exogenous ketones and behavior effects.
@JoshuaTGaines @GuidoFrank @UCSDMedSchool Great thought! We are still working to understand the exact mechanisms but this is essentially the theory that Dr. Frank has proposed. It would be interesting to see what role exogenous ketones could play, and future research can address this.
New study offers hope for anorexia nervosa. The first-ever pilot trial of ketogenic therapy for anorexia nervosa was just published. Here's what @GuidoFrank and his research team at @UCSDMedSchool found. 🧵
A pilot study published today in @CommsMedicine demonstrates the potential for a new approach to treating anorexia nervosa. The research from @UCSDMedSchool, led by @GuidoFrank, reports that a ketogenic nutritional intervention was feasible and safe for patients with weight-normalized anorexia nervosa. Significant improvements were observed in eating disorder symptoms, with nearly 3 in 4 of study completers no longer meeting criteria for an anorexia nervosa diagnosis, and all completers experiencing an improvement in depression scores. “This study highlights the promise of dietary interventions that target underlying neurometabolic dysfunction for even the most intractable psychiatric conditions like anorexia nervosa,” said @janellison, co-founder and president of Baszucki Group, which funded the study. “We hope this work drives awareness and support for researching and delivering ketogenic therapy for eating disorders, providing new hope for patients and their families.” Read the paper: doi.org/10.1038/s43856… Read the press release: bit.ly/49EQPyH Learn more about the extension for the study for patients with both anorexia nervosa and bulimia nervosa: bit.ly/3PUK5WS
After just 14 weeks. Results like this are unheard of for #anorexia with standard of care treatments. Bring on the #RCT and so appreciate @GuidoFrank's ground breaking study accumulating evidence to support his existing theory. "By the end of the study, 72% of the participants had EDE-Q and depression scores within the normal range, indicating significant improvements in eating disorder symptoms, including reduced dietary restraint, less concern about food and body shape, and improved mood." doi.org/10.1038/s43856…
Check out our new paper on ketogenic therapy for anorexia nervosa! Our findings provide early evidence that ketogenic therapy may become a treatment for anorexia nervosa, a severe psychiatric disorder for which no biological treatment currently exists. nature.com/articles/s4385…
Please consider attending Keto-Life, Leading Your Way To Metabolic Health, in beautiful St. Moritz! 😊 keto-live.com
@janellison @CaitlinHoe62870 A must-see film on the power of diet and health! This is a fascinating and highly relevant film, engaging, accessible, and filled with groundbreaking insights into how diet shapes both mental and physical health. Incredibly intriguing!
After a three year labor of love, our film, The Cholesterol Code, is streaming on Amazon. You can help by buying or renting it on Amazon (for less than $3), watching it, then leaving an honest rating and review. Early traction gives us the best chance of getting picked up by Prime. The film features individuals in our community who have healed from mental illness using ketogenic therapy, only to find their LDL cholesterol jump, raising concerns from the medical establishment about the risk of heart disease. Do we really want people who no longer experience mania, psychosis, depression, anxiety, hallucinations, or delusions to stop keto because of one lab number? For those of us involved in the metabolic mental health movement, that is the key question this film asks--and it's a question the scientific community must take seriously. Lives depend upon it. Watch it, rate it, and share it with all your friends!
🚨 🚨 🚨OUR DOCUMENTARY IS HERE 🚨 🚨 🚨 🎥 Our film The Cholesterol Code dropped on Amazon! (Link next tweet) 🔥Personal stories of healing with keto 🔬New insights on Cholesterol 🫀Our groundbreaking study on heart disease 🙏 Please watch, share & leave an honest review! 🙏
Medications don't treat anorexia, but zinc might, and CBD improved weight in this first placebo controlled trial: ▪ Small, barely positive ▪ Has a theoretical basis Full details: psych-partners.com/cbd-for-anorex…
Find a screening and see our film! So fun to be at the world premiere in Las Vegas with my son @matthewbaszucki and @realDaveFeldman and @jenisenhart and colleagues from @Metabolic_Mind. The standing ovation was well earned. Screenings are only going on for the next couple months, so don't miss your chance.
Saturday night in Las Vegas, #THECHOLESTEROLCODE took the stage at The Beverly Theater. Our special screening event brought together a room of people who are moving this film forward — one city, one town at a time. Attend a screening near you, be a part of this movement:
Can a keto diet "cure" serious mental illness? Here's my piece published today in @sfchronicle. "OPINION: Diagnosed with bipolar disorder, my son began a medically supervised ketogenic regimen — and it sent his symptoms into lasting remission, Jan Ellison Baszucki writes." To read the full oped, just enter your email when prompted for the gift link: tinyurl.com/3kwrcxyu In response to comments from HHS Secretary, Robert F. Kennedy Jr., I share our family's story about how after half a decade of illness, ketogenic therapy has kept my son's bipolar I disorder symptoms in remission since 2021. I include the latest on the emerging science and practice of this therapeutic approach. "Has my son been 'cured'? It’s not a term we use in our work, and it’s also not the most important question. The more pressing concern is whether we are willing to rigorously test promising new treatment approaches when conventional care has failed far too many." @Metabolic_Mind @ChrisPalmerMD @BaszuckiGroup @matthewbaszucki @DavidBaszucki @metcoalition @LWSchizophrenia
How can doctors, psychiatrists, and other health practitioners implement keto for serious mental illnesses like schizophrenia, bipolar disorder, and depression? In this short interview, @bschermd sits down with Dr. Georgia Ede to discuss a newly published Delphi consensus paper in Frontiers in Nutrition, authored by eight experienced clinicians and researchers to establish best practices for the use of ketogenic metabolic therapy (KMT) in serious mental illnesses. 📚 Read the Paper: Published in Frontiers in Nutrition: doi.org/10.3389/fnut.2… Special shoutout to the 8 authors of this paper which include: @georgiaedemd, Dr. Matthew Bernstein, @loricalabresemd, @iaincampbellphd, @ketocounselor, @chrispalmermd, @shebanimd, and @kaniazupec
Do you know someone in Germany suffering from PTSD? They may qualify for participation in this study to assess whether the ketogenic diet might help. Core eligibility requirements include the following criteria: - Adults (18–65 years) - Verified PTSD diagnosis according to DSM-5-TR or ICD-11 - Currently living in Germany - High treatment motivation - Not already following a ketogenic diet within the past 6 weeks - No changes to psychiatric medication regimen in the past 6 weeks Interested patients can reach out via a brief email at [email protected]. Full study information: clinicaltrials.gov/study/NCT07415…
💊⚖️ Psychiatric medications can be life-changing. They can also quietly drive metabolic complications like high blood pressure, weight gain, insulin resistance, and abnormal cholesterol and triglycerides. All of which can reduce the quality of, or even shorten, our patients' lives. Knowing how to detect and treat these complications can be life-saving. That's why we’re excited to share our newest FREE CME course: The Metabolic Consequences of Psychiatric Medications and Options for Management Instructed by Dr. Matthew Bernstein and @ProfDeannaK. 🔗 mycme.com/courses/metabo…
“Are you okay?” Everyone kept asking Adnan that question…right as he was finally starting to feel alive again. In this deeply personal story, Adnan Alkhalili shares his transformation from a high school student overwhelmed by OCD, anxiety, and panic attacks…to a thriving young adult who found freedom through metabolic health. His journey wasn’t fueled by medication. It was driven by radical lifestyle change, starting with a ketogenic diet, movement, and reconnecting with what it means to be human. 🎓 From missing school due to daily panic attacks to launching a mental health initiative and reclaiming his identity, Adnan’s story challenges the conventional approach to youth mental health. 💡 Key themes in this video: - Living with undiagnosed OCD and panic disorder in high school - Feeling “stuck in a cage” and breaking free with diet and lifestyle interventions - How nutrition, light, movement, and mindset transformed his brain and body - Why lived experience should guide the conversation around mental health care 🙌 “Try to be human first.” That’s the invitation at the heart of Adnan’s story. Adnan’s story contributes to a growing body of evidence demonstrating that ketogenic therapy can be a potential treatment option for young adults living with depression, anxiety, and other serious mental illnesses. To learn more, visit our Youth Mental Health Hub: metabolicmind.org/resources/topi… Resources: - Learn more about the THINK+SMART framework: a self-guided, community-based framework that helps you develop a customized metabolic approach to mental health: thinksmart.metabolicmind.org - To learn more about Adnan’s personal journey, check out her full THINK+SMART profile: metabolicmind.org/thinksmart/exp…
What if many psychiatric disorders share the same hidden glitch in how the brain infers reality? In a new volume, @AlPowers7 and I gather experts to examine how disrupted sensory inference across #vision, #touch, #proprioception and #interoception might unify our understanding.
We are thrilled today to introduce THINK+SMART, a new community-inspired tool from Metabolic Mind designed to help individuals take control of their mental health. THINK+SMART is an acronym that describes a metabolic approach to mental health. THINK stands for therapeutic integration of nutritional ketosis. SMART stands for sleep, move, avoid, rebuild, and track. Together, these provide a framework for implementing personalized ketogenic and metabolic therapies to combat mental illness. Imagine being in the driver’s seat of your mental well-being, guided by cutting-edge clinical expertise and research from experts like @ChrisPalmerMD, @GeorgiaEdeMD, @KetoCounselor, @IainCampbellPhD, and @MitoPsychoBio and inspired by stories of resilience from those who’ve walked this path like @MsMiaMendez, @LWSchizophrenia, @bright_har6612, @DrEricRodgers, @Carobeckwith, @JourneyofHope4U, @iam_emilyanne, @BaszuckiMatt, @robynrdobbins, Steven T, Wesley Braden, Donika Hristova, and more. This is what THINK+SMART provides! Whether you’re a practitioner or someone living with a psychiatric disorder, we hope THINK+SMART will serve as a resource for improving metabolism to improve your overall physical and mental health. Visit metabolicmind.org/think-smart to learn more.
Pragmatic idealists in the #metabolicpsychiatry movement sustain and build energy, keeping the vision of recovery alive while working within current systems to make progress possible for patients and practitioners alike.
Huge thanks to all who have responded thus far. One day left to share your experiences using ketogenic diet therapy to help taper or reduce side effects of psych meds. youtube.com/playlist?list=… Link above for our playlist on keto and psych meds, which may be helpful for some following this thread.
We want to do more content on the topic of food/med interactions, as well as tapering meds while on a therapeutic ketogenic diet. We would love to understand who has tried this and how it went. If you have experience tapering psychiatric meds while on a therapeutic ketogenic
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Stanford Eating Disor... @EDResearch
5K Followers 100 Following Hosted by Stanford University School of Medicine's Eating Disorder Research Program: A resource for eating disorder (ED)-related information
EmbarkLab @EmbarkLab
413 Followers 64 Following We are the EMBARK lab at the University of Texas at Austin. We study eating-related methodology, behaviors and risk. Directed by Dr. Katherine Schaumberg
F.E.A.S.T. @FEAST_ED
5K Followers 1K Following We are the global organization of carers of people with eating disorder diagnoses. Empowering families and promoting evidence-based treatment!
Angela Guarda M.D. @AngelaGuarda
242 Followers 81 Following Director of Eating Disorders Program, Johns Hopkins Hospital. @JohnsHopkins_ED
UC San Diego Health E... @UCSD_EDC
3K Followers 1K Following International leader in #EatingDisorders research & treatment. Providing treatment for adults, teens & children. Do not hesitate to reach out to us now!
Eating Disorders Coal... @EDCoalition
8K Followers 905 Following The federal advocacy organization for eating disorders
Beat @beatED
49K Followers 973 Following Beat is the UK's eating disorder charity. For support 👉 contact our Helpline via 0808 801 0677, email [email protected] or DM our socials.
Pamela Keel @DrPamKeel
1K Followers 423 Following Scientist, author, psychology professor, eating disorders researcher, she/her
















