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Are you interested/building in AIxBio? Are you in Bangalore? Me, @anaturalist and @vinayprabhu are organising "AIxBio BLR" at IISc this Saturday, April 25th at 11:30 AM. The goal? Build the community that is missing and help each other in any way possible. We have Founders, PhDs, Faculty, PostDocs attending the event. If you are building something in the space or have a unique expertise, we would love to have you. Register on the link below.
UPDATE: LLMs in biology still have some way to go. A few weeks ago, I had said that @AnthropicAI models are the best at creating publication level figures. But while adding image support to PyMolAI, I realized that is not the case. Left: A simple pose from a paper I wanted to recreate. Right: What Sonnet 4.6 was able to make. They don't look similar at all. "instead of knowing what a good pose is, the models just know the steps to get to a good pose" What this means is, that the models don't understand molecular/protein structures. They just have been trained on enough pymol commands to get to a good point. Anthropic models more so than others.
I tested models from @AnthropicAI @OpenAI @Google @Zai_org @MiniMax_AI and @Kimi_Moonshot on whether they can create a publication-level view of a protein-ligand binding site and the results were surprising. TL;DR: Anthropic models did the best and Gemini models did the worst.
OpenBio skills can be used anywhere! Give your agents the power to research.
Your biology research just got a co-pilot. Meet the @OpenBioAI skill 🌸
Your biology research just got a co-pilot. Meet the @OpenBioAI skill 🌸
I tested models from @AnthropicAI @OpenAI @Google @Zai_org @MiniMax_AI and @Kimi_Moonshot on whether they can create a publication-level view of a protein-ligand binding site and the results were surprising. TL;DR: Anthropic models did the best and Gemini models did the worst. Task was simple: "Load 5DEL and create a publication ready view of the ORO and FMN binding site" Here are the results: 1. Sonnet 4.6 from @AnthropicAI: - Fast - Used the tools pretty well - Created the best view with clear labelling and color choices - always felt in control of what it was going for - very impressed
I am Open-Sourcing PyMolAI! Meet PyMolAI, an AI agent that can talk to your protein structures. Built on top of PyMOL, PyMolAI lets you interact with your structures in plain language. Whether you're: - Analyzing protein structures - Aligning complexes - Creating
I am Open-Sourcing PyMolAI! Meet PyMolAI, an AI agent that can talk to your protein structures. Built on top of PyMOL, PyMolAI lets you interact with your structures in plain language. Whether you're: - Analyzing protein structures - Aligning complexes - Creating publication-ready figures - Or running design workflows PyMolAI interprets your request, executes the necessary PyMOL commands, and manages the workflow for you. It integrates with @OpenBioAI APIs, giving you access to tools like Boltz, ProteinMPNN, and BoltzGen — directly from your PyMOL session. It has local chat history with session syncing, so you can pick up exactly where you left off.
Shipped some improvements to the visual summaries in @OpenBioAI. It will feel nicer overall, I am loving it.
We have updated the default MAX model on @OpenBioAI from Sonnet 4 (which I really liked) to Sonnet 4.5, because of the API issues from Anthropic's side. There were a lot of errors when using Sonnet 4. I feel they're realigning resources for newer models. Sonnet 4.5 is pretty solid, tends to take more notes. But should feel a lot more smoother, have been testing it a lot past couple of days. Anyways if you tried out OpenBio in the past couple of days and faced issues, please give it a try again. Lots of cool stuff otw and already there.
OpenBio viewers update! I had this one in mind since I started @OpenBioAI , but when @ATinyGreenCell said that I should add it, I had to. Now you can view your ✨pretty plasmids✨ in OpenBio. Openbio supports all the common formats like Genbank and SnapGene. This update comes with improvement to existing fasta file viewers along with a new MSA viewer. Have a look:
Loving @OpenBioAI right now. I lowkey feel we have nailed it with the UI.
I am hosting a session at @ns Library on 16th Feb on Protein Language Models and their applications. Come over if you're around.
Announcing OpenBio skills and APIs for your Agents and Molts🦀! Over the past few days we've seen how far agents have come, they're doing everything from making payments to making religions. Now we want to empower them to do biology research. From drug discovery to literature search, get your agents to do anything for you. Works with any of your favourite agent platform @openclaw @mograxyz @claudeai @opencode and more! Set it up now!
Now @OpenBioAI creates a visual summary for you at the end of an analysis. Go check it out, I find it very helpful.
Using @OpenBioAI from @opencode feels good
the more i use @OpenBioAI , the more frustrated i get that no one told me about this sooner. where has this been all my life?
Building OpenBio is so fun! This feature has been on prod since December but we only got around to talking about it now. So much more is already there that we have not talked about and so much more is on the way!
Pipette in hand? Busy running experiments? Now you can talk to OpenBio to run your analysis. Try it out now!
Vivien Perrelle @PerrelleVivien
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kyo @kyomangold
113 Followers 2K Following building in physical ai 👨🏻💻 | @unumlabs_ai | going from 0 to … 🚀 | ai/ml & robotics | eth zurich alum🇨🇭
Headbanger @SaurabhSharma_I
80 Followers 205 Following Designer and Devloper | #100xDevs | Read my Blogs at https://t.co/Alfe0XzlKs | more on https://t.co/NRFnLjT1MT
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38 Followers 205 Following Studying T cell immunotherapy at Baylor College of Medicine.
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132 Followers 541 Following
Rishu Kumar @rishdotuk
842 Followers 1K Following Long document understanding, Multilingual Evals and efficient models mainly, but other #NLProc applications in free time | vim enthusiast
Nitanshu (pqc/acc) @NitanshuL
3K Followers 3K Following encryptionist @encifherio prev @MathWorks — pqc, aviation, physics
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2 Followers 759 Following
Charvi Sethi @charvispeaks
5K Followers 634 Following software engineer @amazon | 23 | you’ll find me either building or touching the grass 🌻
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1K Followers 2K Following Bringing more users to crypto! | product @Polymer_Labs | ex @SOCKETProtocol |
BullOnMoon @BullOnMoon
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fyruz @FyruzOne
304 Followers 409 Following / biology - Msc + PhD soon / gut microbiome research / genomics, LLMs, biostatistics
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Shagunn @shagunuppls
834 Followers 1K Following Brainstorming with bots 🤖🧠 @SkildAI || MS Robotics @CarnegieMellon @CMU_Robotics || Previously: @Preimage_AI | CLVR Lab @USC | BRAIN Lab @SUTDsg | @iiitdcai
Mihir Sharma (Curovan... @mihircurovana
61 Followers 748 Following part-time doctor, full-time co-founder and CEO (larper) @curovana.
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Ravi Sharma @ravishar313
4K Followers 1K Following Computers | Biology | IITB | Building Cursor for Biology @OpenBioAI | @upsurgelabs | Check out: https://t.co/GXLQhRNyq8
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