The MOG Project @TheMOGProject
We collaborate with national & international Doctors & Researchers around the world to help educate & provide research about #MOGAD. 501(c)3 🌺 #ViewsAreOurOwn mogproject.org United States Joined April 2020-
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The Italian Registry for Autoimmune Encephalitis 🇮🇹 was presented for the first time in the beautiful setting of Alghero! Thanks to all the friends and colleagues from allover Europe for making this possible💣 @neurotutto @AlvinoBisecco @MGastaldi85 @GruppoNina
Last week, leading international experts in #MOGAD research & care gathered in Cambridge, Massachusetts for the International Expert Panel on Research Directions in MOGAD — bringing together leading clinicians, researchers, industry collaborators, & @TheMOGProject’s patient advocacy leadership to help align future priorities in MOGAD. Discussions focused on: ✅diagnostics ✅biomarkers ✅therapeutics ✅quality of life ✅patient experiences ✅future research directions — with outcomes serving as an important document of record for The MOG Project’s global advocacy & policy work. The panel was co-chaired by Julia Lefelar, Lisa Ryan & Leslie Hanrahan from @TheMOGProject & Dr @mlevy18 from @MGHNeurology. f Thank you to our sponsors, @UCBMedia & @Roche Read more: mogproject.org/international-… We wonder if you can find your picture somewhere in the link 🤪 @Mayo_AING @EthelScl @LisaKRyan @mlevy18 @GabrielaRomanow @chenmayo @EoinFlanagan14 @ESotirchos @EliaSechi @darshi_r @FabienneBrilot @IzzyCotter & many more!
Exciting study showing that IGLON5 antibodies induce neurodegenerative signatures in vitro science.org/doi/10.1126/sc… This fits with the sequential human pathology in the same disease academic.oup.com/brain/article/…
Great OCT study from @HopkinsMedicine @ESotirchos Although AQP4+NMOSD causes worse optic neuritis outcomes than MOGAD, ganglion cell loss from retrograde degeneration seems similar, both greater than #MultipleSclerosis! 👀 So what drives worse vision in AQP4+NMOSD? #NMOSD #MOGAD
Honored to be with the leaders who recognized #MOGAD as a distinct entity, young investigators paving the future, and patient advocacy groups making a difference! My 🩷🙌 Gabriela Romanow @mlevy18 @TheMOGProject for a conference as bright as the gorgeous day we shared in Boston!
This weekend, we’re honored to convene leading international experts in #MOGAD research & care for the International Expert Panel on Research Directions in MOGAD in Cambridge, Massachusetts! Together, global clinicians, researchers, advocates, & industry leaders will collaborate to help shape the future of #MOGAD research, treatment development, and patient care. We’re especially excited for discussions focused on: 🔹 Worldwide disease patterns and diagnostic access 🔹 Mechanistic and biomarker research priorities 🔹 Future approved therapeutics for MOGAD 🔹 Quality of life, cognitive and behavioral health, and long-term outcome research 🔹 The patient experience and its critical role in shaping future research directions A major goal of this meeting is to identify the field’s most urgent research gaps and future priorities — work that will help guide advocacy efforts, regulatory decision-making, and the development of a publishable consensus paper for a leading neurology journal. We’re deeply grateful to the incredible experts and patient voices contributing to these conversations, and to our sponsors, including UCB Biopharma and Genentech, a member of the Roche Group, for supporting this important gathering. We look forward to sharing more from the weekend ahead! @FabienneBrilot @darshi_r @IzzyCotter @mlevy18 @MGHNeurology @ucb_news @Roche @Mayo_AING
@nodisability @EoinFlanagan14 We’ve asked the same questions so have our patients. Better for it only to be done for research purposes. It shouldn’t be the be all and end all and definitely shouldn’t be the first thing considered during an attack either.
A case report of Enteroviral encephalitis in a 37 year old woman taking kesimpta for multiple sclerosis. IgG was normal and IgM was low. MRI brain (image) shows symmetrical lesions in the thalamus. She improved but with ongoing neuropsychiatric symptoms journals.sagepub.com/doi/10.1177/13…
MOGAD frequently presents as cortical encephalitis and ADEM phenotypes with seizures and encephalopathy. Saini et al presented a case who presented with an extremely rare bilateral opercular syndrome phenotype (without seizures). #MOGAD @neuro_ian Link: 10.4103/aian.aian_1315_25
This proof-of-principle study demonstrates a rapid optofluidic approach to rapidly identify patient-derived monoclonal antibodies against conformational membrane antigens, such as those in #MOGAD: hubs.la/Q04fvWyk0
Reports of the clinician’s demise are greatly exaggerated! Happy to share this editorial, led by Dr. Buciuc, on study “MOG-IgG Positivity Does Not Equal MOGAD.” Antibody positivity and criteria are powerful tools but they do not replace clinical judgment👇thejcn.com/DOIx.php?id=10…
Maintenance Immunotherapy in MOGAD: Early Steroid Benefit, Dose Thresholds, and Disability Risk - Part 3 neurologyminute.libsyn.com/maintenance-im…
@EoinFlanagan14 Great paper! Clinical judgements have always helped our patients especially with strong relationships with their doctors
@darshi_r We will miss you😢 Enjoy the transition Darshi
Maintenance Immunotherapy in #MOGAD #NeurologyMinute @AANmember neurologyminute.libsyn.com/maintenance-im… 🎙️There is strong evidence that ≥12.5 mg/day (0.16 mg/kg/day paediatric) corticosteroids for 5 months from MOGAD onset reduces risk of relapse and permanent disability📉 #Neuroimmunology
A patient presents with reduced vision, color desaturation and pain on eye movements. What is your favored diagnosis? View my Radiopaedia Case Read and get up to 0.25 AMA PRA Cat 1 Credits: radiopaedia.org/courses/case-r…
Autoimmune encephalitis: what the radiologist needs to know link.springer.com/article/10.100…
#FLAMES, desafío diagnóstico. Fenotipo atípico de #MOGAD 1️⃣ Crisis epilépticas 2️⃣ Cefalea refractaria 3️⃣ Encefalopatía Simulando un cuadro infeccioso agudo RM: lesiones ⬆️intensas T2 cortical y unilateral Confirmación por CBA MTP precoz #Neuroinmunologia #NeurologiaClinica
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12 Followers 92 Following Jesus is my life. Isaiah 40:31. Revelation 21:5 I'm a Mogger: Diagnosed with MOG in 2024 Donate to The MOG Project https://t.co/0iMUFlC7JH Also Roll Tide, Roll!
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